Dave, showing why he might be the best historian-blogger in the universe, today uncovered a 1960 comic produced by George Wallace's successful campaign for Alabama governor. The site has numerous other links to comics with social issues. Some of the labeling is not good, particularly on the early ones. But they are mostly pretty awesome. See for instance this 1956 comic from Planned Parenthood. Or this one about the dangers of huffing chemicals. It's really pretty freaking mind-blowing. In fact, the whole site is a great archive of teaching material, not just the comics.
In the comments on Dave's post, Morinao points us to this 1970 Superman comic when Lois Lane becomes a black woman in order to fight racism.
My mind is totally blown.